Our Science

Cardiovascular disease — the world’s biggest killer

  • Globally, cardiovascular disease kills 18 million people each year, and the burden is increasing
  • In 2019, 8.9 million people died from heart attack and 6.2 million from stroke
  • There are no drugs available to prevent the tissue injury caused by stroke and heart attack
  • Patients with advanced heart failure may require heart transplantation, but there is a shortage of donor hearts
  • Huge unmet medical need for safe and effective cardioprotective and neuroprotective drugs

Ischemia* kills heart muscle cells and brain neurons

Brain acidosis during stroke leads to death of neurons

Our solution: preventing cell death provoked by tissue acidosis