
Cardiovascular disease — the world’s biggest killer
- Globally, cardiovascular disease kills 18 million people each year, and the burden is increasing
- In 2019, 8.9 million people died from heart attack and 6.2 million from stroke
- There are no drugs available to prevent the tissue injury caused by stroke and heart attack
- Patients with advanced heart failure may require heart transplantation, but there is a shortage of donor hearts
- Huge unmet medical need for safe and effective cardioprotective and neuroprotective drugs
Ischemia* kills heart muscle cells and brain neurons

Brain acidosis during stroke leads to death of neurons


Our solution: preventing cell death provoked by tissue acidosis

